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Invitrogen™ JSRP1 Polyclonal Antibody
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100 μL
Unit Size:
100µL
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15768631 100 μL 100µL
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Product Code. 15768631 Supplier Invitrogen™ Supplier No. PA560811

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EAEVRPKIPG SREAAENDEE EPGEATGEAV REDRVTLADR GPKERPRREG KPRKEKPRKE ERPKKERPRK EER Highest antigen sequence identity to the following orthologs: Mouse - 42%, Rat - 48%.

The junction between the transverse tubules (T-tubules) and the sarcoplasmic reticulum (SR) of skeletal muscle is called the triad. At the triad, dihydropyridine receptors (DHPR) of the T-tubule serve as voltage sensors in excitation-contraction coupling, while ryanodine receptors (RyR), the calcium release channels, exist in the membrane of the terminal cisternae of the SR. It is thought that during slow phase depolarization of the T-tubule, a third protein, triadin (95 kDa) transmits electrochemical signals to the SR through direct interaction with both DHPR and RyR. Another skeletal muscle specific 90 kDa protein has also been localized to the this junction. This protein is phosphorylated by an intrinsic protein kinase in triads suggesting that it may play an important regulatory or structural role in the skeletal muscle triad junction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JSRP1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene JSRP1
Gene Accession No. Q96MG2
Gene Alias 2300003C06Rik; 2310032K21Rik; homolog of mouse skeletal muscle sarcoplasmic reticulum protein JP-45; JP45; JP-45; Jsrp1; Junctional sarcoplasmic reticulum protein 1; Junctional SR; junctional-face membrane protein of 45 kDa homolog; skeletal muscle sarcoplasmic reticulum protein JP-45
Gene Symbols JSRP1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human JSRP1. Recombinant protein control fragment (Product #RP-99141).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 126306
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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