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JAM-A (CD321) Monoclonal Antibody (H202-106), Biotin, Invitrogen™
Rat Monoclonal Antibody
Brand: Invitrogen MA181733
Additional Details : Weight : 0.01000kg
Description
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. Rat anti Mouse CD321 antibody, clone H202-106 recognizes murine CD321, also known as junctional adhesion molecule 1 (JAM-1). CD321 is a 274 amino acid approximately 32-4 1kDa single pass, type I transmembrane glycoprotein, which shares similarities with related proteins JAM-2 and JAM-3.
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.Specifications
JAM-A (CD321) | |
Monoclonal | |
0.1 mg/mL | |
PBS with 1% BSA and 0.09% sodium azide; pH 7.4 | |
O88792 | |
F11r | |
MTE1/MTE2 stromal cell lines. | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG1 |
Flow Cytometry | |
H202-106 | |
Biotin | |
F11r | |
9130004G24; AA638916; BV11 antigen; CD321; ESTM33; F11 R; F11 receptor; F11 receptor/F11R; F11R; JAM; JAM1; JAM-1; JAMA; JAM-A; Jcam; Jcam1; junction cell adhesion molecule A; junction cell adhesion molecule1; junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM-1; Platelet adhesion molecule 1; platelet F11 receptor; UNQ264/PRO301 | |
Rat | |
Protein G | |
RUO | |
16456 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |