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Invitrogen™ JAB1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529872

Product Code. 13494207

  • 516.00 € / 100µL

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Description

Description

Recommended positive controls: HeLa, mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (99%), Xenopus laevis (99%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the 'Signalosome', which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

JAB1
Polyclonal
Unconjugated
Cops5
38 kDa Mov34 homolog; AI303502; COP9 (constitutive photomorphogenic) homolog, subunit 5; COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana); COP9 complex S5; COP9 constitutive photomorphogenic homolog subunit 5; COP9 signalosome complex subunit 5; COP9 signalosome subunit 5; Cops5; CSN5; JAB1; Jun activation domain-binding protein 1; Jun coactivator; Kic2; Kip1 C-terminus-interacting protein 2; MGC3149; Mov34; MOV-34; SGN5; signalosome subunit 5; testis secretory sperm-binding protein Li 231m
Rabbit
Antigen affinity chromatography
RUO
10987, 26754
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.35 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
O35864, Q92905
Cops5
Recombinant protein encompassing a sequence within the center region of human Jab1. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse
Antibody
IgG
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