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Indibulin, MedChemExpress

Product Code. 16471947
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Product Code. 16471947

Brand: Medchem Express HY13649

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Description

MedChemExpress Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis.

Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis.

Specifications

Chemical Name or Material Indibulin
CAS 204205-90-3
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C22H16ClN3O2
Quantity 50 mg
Synonym ZIO 301 D 24851
Solubility Information DMSO : 50 mg/mL (128.26 mM; Need ultrasonic)
SMILES O=C(NC1=CC=NC=C1)C(C2=CN(CC3=CC=C(Cl)C=C3)C4=C2C=CC=C4)=O
Molecular Weight (g/mol) 389.83
Formula Weight 389.83
Percent Purity 99.47%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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