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IMR-1, MedChemExpress

Product Code. p-200098429
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16423018 10 mg 10mg
16414326 100 mg 100mg
16409586 50 mg 50mg
16405757 5 mg 5mg
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Product Code. 16423018 Supplier Medchem Express Supplier No. HY100431

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Description

MedChemExpress IMR-1 is a novel class of Notch inhibitor targeting the transcriptional activation with an IC50 of 26 μM. IMR-1 prevents the recruitment of Mastermind-like 1 (Maml1) to the Notch Ternary Complex (NTC) on chromatin, inhibits Notch target gene transcription and dramatically inhibits tumor growth.

IMR-1 is a novel class of Notch inhibitor targeting the transcriptional activation with an IC50 of 26 μM. IMR-1 prevents the recruitment of Mastermind-like 1 (Maml1) to the Notch Ternary Complex (NTC) on chromatin, inhibits Notch target gene transcription and dramatically inhibits tumor growth.

Specifications

Chemical Name or Material IMR-1
CAS 310456-65-6
Color Yellow
Purity Grade Notes Research
Molecular Formula C15H15NO5S2
Quantity 10 mg
Solubility Information DMSO : ≥ 100 mg/mL (282.96 mM)
SMILES O=C(OCC)COC1=CC=C(/C=C(SC(N2)=S)\C2=O)C=C1OC
Molecular Weight (g/mol) 353.41
Formula Weight 353.41
Percent Purity 98.88%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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