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Invitrogen™ Human IL-4 ELISA Kit, High Sensitivity

Product Code. 18051673
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Quantity:
96 Tests
Unit Size:
Pack of 96
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18051673 96 Tests Pack of 96
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Product Code. 18051673 Supplier Invitrogen™ Supplier No. BMS2252HS

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Description

ELISA

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P05112
Assay Range 0.25 to 16.0 pg/ml
Assay Sensitivity 0.1 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 3565
Gene Symbol Il4
Interassay CV 11%
Intraassay CV 8.8
Kit Contents Pre-coated microwell plate, Biotinylated Detection Antibody, Streptavidin-HRP, Standard, Sample Diluent, Assay Buffer Concentrate, Amplification Reagent I, Amplification Reagent II, Wash Buffer Concentrate, Substrate Solution, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target IL-4
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs
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