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IL-10 Monoclonal Antibody (JES3-9D7), Invitrogen™

Rat Monoclonal Antibody

Brand:  Invitrogen AHC0102

Additional Details : Weight : 0.50000kg

Product Code. 10008602

  • 470.00 € / Each
Estimated Shipment: 17-06-2024
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For Research Use Only. All usage must comply with product instructions.


Description

Description

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
Specifications

Specifications

IL-10
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P22301
IL10
Recombinant human Interleukin 10.
500 μg
Primary
Human
Antibody
IgG1 κ
ELISA, Flow Cytometry, Neutralization
JES3-9D7
Unconjugated
IL10
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
Rat
purified
RUO
3586
-20°C
Liquid
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