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Invitrogen™ IARS Polyclonal Antibody

Description
IARS Polyclonal Antibody for IHC (P), Western Blot
IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
Specifications
Specifications
| Antigen | IARS |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.7 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Gene | IARS1 |
| Gene Accession No. | P41252 |
| Gene Alias | 2510016L12Rik; AI327140; AU044614; E430001P04Rik; fi46h05; FLJ20736; IARS; IARS1; Iarsl; ILERS; ILRS; IRS; isoleucine tRNA ligase 1, cytoplasmic; isoleucine tRNA synthetase; isoleucine--tRNA ligase, cytoplasmic; isoleucine-tRNA synthetase; isoleucyl tRNA synthetase; isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase 1; isoleucyl-tRNA synthetase, cytoplasmic; PRO0785; wu:fi46h05; zgc:63790 |
| Gene Symbols | IARS1 |
| Show More |
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