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Invitrogen™ Human ZIP1 Synthetic Peptide

Product Code. 15285179
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Quantity:
50 μg
Unit Size:
50µg
This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Product Code. 15285179

Brand: Invitrogen™ PEP1180

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This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Description

Synthetic Peptide

ZIP1 Synthetic Peptide, PEP-1180, from Invitrogen.

ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-kappa-B, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 27173
Species Human
Purification Method purified
Accession Number Q9NY26
Common Name Human ZIP1
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol SLC39A1
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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