Gibco™ Human TNF-RI (soluble) Recombinant Protein

Description

Human TNF-RI (soluble) Recombinant Protein for Western Blot, IHC, ELISA, Ctrl, FN

sTNF-RI is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NFκB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor.

• High purity: no interference from other proteins or contaminants
• High biological activity: more results with less protein
• Proven compatibility: Gibco proteins bioassayed with Gibco media
• High purity recombinant bioactive protein: to help ensure Gibco growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein
• High biological activity: in-house activity testing of Gibco Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, anti-viral, and protease assays; specific activity is determined by measuring the inhibition of TNF-α mediated cytotoxicity in murine L929 cells in the presence of 0.25ng/mL TNF-α

Approved for shipment at Room Temperature or on Wet or Dry Ice.