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Invitrogen™ Human SPRED1 Synthetic Peptide

Product Code. 15378950
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Quantity:
50 μg
Unit Size:
50µg
This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Product Code. 15378950

Brand: Invitrogen™ PEP0738

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This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Description

Synthetic Peptide

Spred1 Synthetic Peptide, PEP-0738, from Invitrogen.

The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes; it is inhibited by Spred1, a member of the Sprouty family of proteins. Spred1 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 161742
Species Human
Purification Method purified
Accession Number Q7Z699
Common Name Human SPRED1
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol SPRED1
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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