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STEMCELL Technologies Human Recombinant M-CSF
Description
- Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitor cells to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts
- M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues
- It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4
- M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of the placenta, mammary gland, and brain
- M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells
Specifications
Specifications
| Name | Colony stimulating factor 1, CSF-1 |
| Quantity | 10 μg |
| Cell Type | Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Mesoderm, PSC-Derived; Monocytes; Myeloid Cells; Neurons |
| Purity or Quality Grade | ≥95% |
Product Title
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