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STEMCELL Technologies Human Recombinant M-CSF

Product Code. p-7217624
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16244551 10 μg 100µg
17169461 1000 μg 1000µg
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Product Code. 16244551 Supplier STEMCELL Technologies Supplier No. 78057.1

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Macrophage colony-stimulating factor

  • Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitor cells to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts
  • M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues
  • It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4
  • M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of the placenta, mammary gland, and brain
  • M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells

Specifications

Name Colony stimulating factor 1, CSF-1
Quantity 10 μg
Cell Type Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Mesoderm, PSC-Derived; Monocytes; Myeloid Cells; Neurons
Purity or Quality Grade ≥95%
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