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Invitrogen™ Human PLXNA3 (aa 958-1040) Control Fragment Recombinant Protein

Product Code. 30204554
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30204554

Brand: Invitrogen™ RP105119

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66227 (PA5-66227. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P51805
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 55558
Name Human PLXNA3 (aa 958-1040) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 6.3; HSSEXGENE; mKIAA4078; PlexA3; plexin 3; Plexin 4, SEX, homolog to the cMet/HGF receptors; plexin A3; plexin-4; Plexin-A3; Plxa3; Plxn3; Plxn4; Plxna3; Semaphorin receptor SEX; SEX; Sex chromosome x transmembrane protein of HGF receptor family 3; SEXPLEXIN-A3; XAP-6
Common Name PLXNA3
Gene Symbol Plxna3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SSLDAGSRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTA
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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