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Invitrogen™ Human PHAP Synthetic Peptide

Product Code. 15266369
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Quantity:
50 μg
Unit Size:
50µg
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15266369 50 μg 50µg
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For Research Use Only. All usage must comply with product instructions.
Product Code. 15266369 Supplier Invitrogen™ Supplier No. PEP0145
 Restricted Item
Estimated Shipment: 21-08-2026
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For Research Use Only. All usage must comply with product instructions.

Description

Synthetic Peptide

This peptide corresponds to amino acids near the carboxy terminus of human PHAP. PEP-0145 can be used as a blocking peptide with polyclonal antibody PA5-20026.

Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 8125
Species Human
Purification Method purified
Accession Number P39687, Q92688, Q9BTT0
Common Name PHAP
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Alias 2410015B15Rik; 2810018A15Rik; Acid nuclear phosphoprotein 32 (leucine rich); acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; acidic (leucine-rich) nuclear phosphoprotein 32 family, member B; acidic (leucine-rich) nuclear phosphoprotein 32 family, member D; acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic leucine-rich nuclear phosphoprotein 32 family member B; acidic leucine-rich nuclear phosphoprotein 32 family member E; acidic nuclear phosphoprotein 32; acidic nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein 32 family member B; acidic nuclear phosphoprotein 32 family member E; acidic nuclear phosphoprotein 32 family, member A; acidic nuclear phosphoprotein 32 family, member B; acidic nuclear phosphoprotein pp32; Acidic protein rich in leucines; AI047746; AI326868; Anp32; Anp32a; Anp32b; ANP32D; ANP32E; APRIL; C15orf1; cerebellar leucine rich acidic nuclear protein; cerebellar postnatal development protein 1; Cpd1; hepatopoietin Cn; HPPCn; hypothetical protein LOC509685; I1PP2A; inhibitor-1 of protein phosphatase-2A; LANP; LANPL; LANP-L; LANP-like protein; Leucine-rich acidic nuclear protein; leucine-rich acidic nuclear protein LANP; leucine-rich acidic nuclear protein like; MAPM; Mapmodulin; mLANP-L; Pal31; PHAP1; PHAPI; PHAPI2; PHAPI2a; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; PP32; proliferation related acidic leucine rich protein PAL31; proliferation-related acidic leucine-rich protein PAL31; Putative HLA-DR-associated protein I; putative HLA-DR-associated protein I-2; putative human HLA class II associated protein I; silver-stainable protein SSP29; SSP29; vacidic (leucine-rich) nuclear phosphoprotein 32 family, member A; W91701
Gene Symbol ANP32A, ANP32B, ANP32E
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Storage Buffer PBS
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