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Invitrogen™ Human HRG (aa 194-290) Control Fragment Recombinant Protein

Product Code. 30204372
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30204372

Brand: Invitrogen™ RP101204

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (52%), Rat (52%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62989 (PA5-62989. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P04196
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 3273
Name Human HRG (aa 194-290) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias AI265597; AW413091; D16jh2; D18020; DKFZp779H1622; histidine rich glycoprotein; histidine-proline-rich glycoprotein; Histidine-rich glycoprotein; histidine-rich glycoprotein 1; HPRG; HRG; HRG1; Hrgp; THPH11
Common Name HRG
Gene Symbol HRG
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence YFVDFSVRNCPRHHFPRHPNVFGFCRADLFYDVEALDLESPKNLVINCEVFDPQEHENINGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPH
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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