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ACROBiosystems Human DR3 / TNFRSF25 Protein, Fc Tag

Product Code. 15847817
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
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15847817 1 mg 1mg
15837817 100 μg 100µg
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Product Code. 15847817 Supplier ACROBiosystems Supplier No. TN5H52581MG

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Description

Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.5 kDa. The protein migrates as 53-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

Accession Number AAI17190
Molecular Weight (g/mol) 45.5 kDa
Quantity 1 mg
Source Human DR3, Fc Tag (TN5-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Gln 199 (Accession # AAI17190).
Immunogen Gln 25 - Gln 199
Storage Requirements -20°C
Gene Alias TNFRSF25,DR3,APO3,DDR3,TNFRSF12,WSL,WSL1
Common Name DR3 / TNFRSF25
Conjugate Unconjugated
Species Human
Protein Tag Fc Tag
Buffer Tris with Glycine, Arginine and NaCl, pH7.5
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype Other Recombinant Proteins
Purity or Quality Grade >95% as determined by SDS-PAGE
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