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Invitrogen™ Human DENND1C (aa 710-800) Control Fragment Recombinant Protein

Product Code. 30181271
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30181271

Brand: Invitrogen™ RP99238

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (47%), Rat (47%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60105 (PA5-60105. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8IV53
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 79958
Name Human DENND1C (aa 710-800) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias Connecdenn 3; DENN domain containing 1 C; DENN domain-containing protein 1 C; DENN/MADD domain containing 1 C; DENND1C; FAM31C; family with sequence similarity 31, member C; Protein FAM31C
Common Name DENND1C
Gene Symbol DENND1C
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence PSPPESPQILAPTKPNFDIAWTSQPLDPSSDPSSLEDPRARPPKALLAERAHLQPREEPGALNSPATPTSNCQKSQPSSRPRVADLKKCFE
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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