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Invitrogen™ Human CDNF Synthetic Peptide

Produktkod. 15398680
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Quantity:
50 μg
Förpackningsstorlek:
50µg
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15398680 50 μg 50µg
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For Research Use Only. All usage must comply with product instructions.
Produktkod. 15398680 Leverantör Invitrogen™ Leverantörsnummer PEP0547
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Estimated Shipment: 21-08-2026
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For Research Use Only. All usage must comply with product instructions.

Beskrivning

Synthetic Peptide

This peptide corresponds to 12 amino acids near the amino terminus of human CDNF. PEP-0547 can be used as a blocking peptide with polyclonal antibody PA5-20430.

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.
TRUSTED_SUSTAINABILITY

Specifikationer

Gene ID (Entrez) 441549
Species Human
Purification Method purified
Accession Number Q49AH0
Common Name CDNF
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Alias 9330140G23; arginine-rich protein mutated in early stage tumors-like 1; arginine-rich, mutated in early stage tumors-like 1; ARMETL1; ARMET-like protein 1; Cdnf; Cerebral dopamine neurotrophic factor; conserved dopamine neurotrophic factor
Gene Symbol Cdnf
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Storage Buffer PBS
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