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Invitrogen™ Human CCDC22 (aa 284-377) Control Fragment Recombinant Protein

Product Code. 30208140
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Quantity:
100 μL
Unit Size:
100µL
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30208140 100 μL 100µL
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Product Code. 30208140 Supplier Invitrogen™ Supplier No. RP110092

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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145123 (PA5-145123. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CCDC22 is a recently identified coiled-coil domain-containing protein that has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. In rat, CCDC22 has been observed to localize in multiple regions of the brain, including the prefrontal and somatosensory cortex, dentate gyrus and thalamus, and in the ipsilateral motor neurons of the spinal cord after sciatic nerve transection suggesting that it may play a role in neuronal injury response. The human CCDC22 gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability (XLID).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O60826
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 28952
Name Human CCDC22 (aa 284-377) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias AI481216; Ccdc22; ccdc22 {ECO:0000250; coiled-coil domain containing 22; coiled-coil domain-containing protein 22; coiled-coil domain-containing protein 22 {ECO:0000250; CXorf37; DXImx40e; JM1; Ppp1r3f; RGD1560910; RTSC2; Sfc22; UniProtKB:O60826}
Common Name CCDC22
Gene Symbol Ccdc22
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence KTGAPKGSRFTHSEKFTFHLEPQAQATQVSDVPATSRRPEQVTWAAQEQELESLREQLEGVNRSIEEVEADMKTLGVSFVQAESECRHSKLSTA
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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