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Invitrogen™ Human Caspase 13 Synthetic Peptide
Description
This peptide corresponds to 15 amino acids of human Caspase-13. PEP-0074 can be used as a blocking peptide with polyclonal antibody PA5-19949.
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.
Specifications
Specifications
| Gene ID (Entrez) | 8628 |
| Species | Human |
| Purification Method | purified |
| Accession Number | P49662 |
| Common Name | Caspase 13 |
| Concentration | 200 μg/mL |
| Content And Storage | -20°C |
| Description | Synthetic Peptide |
| Format | Liquid |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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