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  4. Invitrogen™ Human B7-H3 (CD276) Fc Chimera Recombinant Protein

Invitrogen™ Human B7-H3 (CD276) Fc Chimera Recombinant Protein

Product Code. 17905591
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
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17905591 1 mg 1mg
17945981 100 μg 100µg
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Product Code. 17905591 Supplier Invitrogen™ Supplier No. RP87954

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Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (500 μL) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV.

CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing. CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q5ZPR3
Concentration 0.25 mg/mL
For Use With (Application) Control, Neutralization
Format Lyophilized
Formulation PBS with 5% mannitol, 5% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Gene ID (Entrez) 80381
Molecular Weight (g/mol) 109.5 kDa
Name Human B7-H3 (CD276) Fc Chimera
pH Range 7.4
Purification Method Purified
Quantity 1 mg
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Endotoxin Concentration <1.0 EU/μg
Gene Alias 4Ig-B7-H3; 6030411F23Rik; AU016588; B7 homolog 3; B7h3; B7-H3; B7RP-2; CD276; CD276 antigen; CD276 molecule; CD276 molecule tv1; costimulatory molecule; PSEC0249; sB7 H3; sB7H3; sCD276; soluble B7 H3; soluble B7H3; soluble CD276; UNQ309/PRO352
Common Name B7-H3 (CD276)
Gene Symbol CD276
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag Fc-tag
Sequence Met1-Thr461
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade >95% as determined by SDS-PAGE.
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