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Invitrogen™ Human ASIC2 (aa 116-190) Control Fragment Recombinant Protein

Product Code. 30205431
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30205431

Brand: Invitrogen™ RP101182

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62554 (PA5-62554. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

ACCN1 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this protein may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q16515
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 40
Name Human ASIC2 (aa 116-190) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias ACCN; ACCN1; ACIC2; acid sensing (proton gated) ion channel 2; acid sensing ion channel 2; acid sensing ion channel subunit 2; acid-sensing (proton-gated) ion channel 2; acid-sensing ion channel 2; Amiloride-sensitive brain sodium channel; amiloride-sensitive brain sodium channel 2; Amiloride-sensitive cation channel 1, neuronal; amiloride-sensitive cation channel 1, neuronal (degenerin); Amiloride-sensitive cation channel neuronal 1; Asic2; ASIC2a; Bnac1; BNaC1a; BNC1; BNC1k; Brain sodium channel 1; degenerin; hBNaC1; Mammalian degenerin homolog; MDEG; MDEG1; MDEG2; neuronal amiloride-sensitive cation channel 1
Common Name ASIC2
Gene Symbol ASIC2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence LLDVNLQIPDPHLADPSVLEALRQKANFKHYKPKQFSMLEFLHRVGHDLKDMMLYCKFKGQECGHQDFTTVFTKY
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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