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Invitrogen™ hnRNP L Polyclonal Antibody
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Product Code. 15934955
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Quantity:
100 μg
Unit Size:
100µg
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15934955 100 μg 100µg
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Product Code. 15934955 Supplier Invitrogen™ Supplier No. PA579383

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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Jurkat whole cell, human MCF-7 whole cell, human PC-3 whole cell, human U87 whole cell, rat liver tissue, mouse liver tissue, mouse RAW2647 whole cell, mouse NIH/3T3 whole cell. IHC: human breast cancer tissue, human colorectal adenocarcinoma tissue, human laryngeal squamous cell carcinoma tissue, human liver cancer tissue, human lung adenocarcinoma tissue, mouse liver tissue, rat liver tissue. ICC/IF: MCF-7 cell.

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen hnRNP L
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene HNRNPL
Gene Accession No. F1LQ48, P14866, Q8R081
Gene Alias C79783; D830027H13Rik; Fblim1; FLJ35509; Heterogeneous nuclear ribonucleoprotein L; heterogenous nuclear ribonucleoprotein L; hnRNP L; Hnrnpl; hnRNP-L; Hnrpl; P/OKcl.14
Gene Symbols HNRNPL
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human HnRNP L (546-571aa LLEWESKSDALETLGFLNHYQMKNPN).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15388, 3191, 80846
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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