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Invitrogen™ HDAC6 Recombinant Rabbit Monoclonal Antibody (2H12)

Description
HDAC6 Recombinant Monoclonal Antibody for Western Blot, IHC (P), ELISA, IP
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Specifications
Specifications
| Antigen | HDAC6 |
| Applications | ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | 2H12 |
| Concentration | 1.15 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | HDAC6 |
| Gene Accession No. | Q9UBN7 |
| Gene Alias | CPBHM; FLJ16239; Hd6; HDA6; Hdac5; Hdac6; histone deacetylase 5; histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6 |
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