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Invitrogen™ HDAC3 Monoclonal Antibody (3G6)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA518069
This item is not returnable.
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Description
Western blot detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Specifications
| HDAC3 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.1% sodium azide | |
| O15379, O88895 | |
| HDAC3 | |
| Human C-terminal peptide (identical in mouse). Sequence: aa 411-428 (NEFYDGDHDNDKESDVEI). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG2a |
| Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 3G6 | |
| Unconjugated | |
| HDAC3 | |
| AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45 | |
| Mouse | |
| Protein G | |
| RUO | |
| 15183, 8841 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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