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Invitrogen™ H3K9me2/H3K14ac Recombinant Rabbit Monoclonal Antibody (RM322)
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Product Code. 17836741
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Quantity:
100 μL
Unit Size:
100µL
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17836741 100 μL 100µL
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Product Code. 17836741 Supplier Invitrogen™ Supplier No. MA544560

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This item is not returnable. View return policy

Rabbit Recombinant Monoclonal Antibody

This antibody reacts to the Histone H3 K27M mutant. No cross reactivity with wild type Histone H3.

Histone H3 is one of the five main histones involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. The term Histone H3 alone is purposely ambiguous in that it does not distinguish between sequence variants or modification state. Histone H3 is an important protein in the emerging field of epigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes.
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Tekniske data

Antigen H3K9me2/H3K14ac
Applications Western Blot, Luminex
Classification Recombinant Monoclonal
Clone RM322
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene H3-3A
Gene Accession No. P84243
Gene Symbols H3-3A, H3-3B
Host Species Rabbit
Immunogen A dimethyl-peptide corresponding to dimethyl-Histone H3 (Lys9) and an acetyl-peptide corresponding to Acetyl-Histone H3 (Lys14). The immunogen range is a synthetic peptide within to aa1-100 of histone H3 in which Lys9 is acetylated.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3020, 3021
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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