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Invitrogen™ H3K9me2/H3K14ac Recombinant Rabbit Monoclonal Antibody (RM322)

Beskrivelse
This antibody reacts to the Histone H3 K27M mutant. No cross reactivity with wild type Histone H3.
Histone H3 is one of the five main histones involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. The term Histone H3 alone is purposely ambiguous in that it does not distinguish between sequence variants or modification state. Histone H3 is an important protein in the emerging field of epigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes.
Tekniske data
Tekniske data
| Antigen | H3K9me2/H3K14ac |
| Applications | Western Blot, Luminex |
| Classification | Recombinant Monoclonal |
| Clone | RM322 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.09% sodium azide |
| Gene | H3-3A |
| Gene Accession No. | P84243 |
| Gene Symbols | H3-3A, H3-3B |
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Produkttitel
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