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  5. Tocris Bioscience™ GW 501516

Tocris Bioscience™ GW 501516

Product Code. 18794719
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18794719 50 mg 50mg
18753168 10 mg 10mg
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Product Code. 18794719 Supplier Tocris Bioscience™ Supplier No. 5674/50

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952.00 EUR valid until 2026-03-31
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Description

Potent and selective PPARδ agonist

GW 501516 is a potent and selective PPARδ agonist (EC50 = 1.2 nM). Displays <1000-fold selectivity over other PPAR subtypes. Increases ABC A1 transporter expression and induces apolipoprotein A1-mediated cholesterol efflux in vitro. Also increase serum HDL cholesterol and lowers small, dense LDL levels in obesity in vivo models.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid
CAS 317318-70-0
Quantity 50 mg
Target PPAR delta Receptor Agonists
Molecular Formula C21H18F3NO3S2
Formula Weight 453.5
Purity >98%
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