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Tocris Bioscience™ GW 501516

Potent and selective PPARδ agonist

Brand:  Tocris Bioscience™ 5674/50

Encompass

Product Code. 15797036

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Description

Description

GW 501516 is a potent and selective PPARδ agonist (EC50 = 1.2 nM). Displays <1000-fold selectivity over other PPAR subtypes. Increases ABC A1 transporter expression and induces apolipoprotein A1-mediated cholesterol efflux in vitro. Also increase serum HDL cholesterol and lowers small, dense LDL levels in obesity in vivo models.
Specifications

Specifications

2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid
317318-70-0
50 mg
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