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  5. Tocris Bioscience™ GSK 2795039

Tocris Bioscience™ GSK 2795039
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Product Code. 18767456
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18767456 25 mg 25mg
18737566 5 mg 5mg
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Product Code. 18767456 Supplier Tocris Bioscience™ Supplier No. 6848/25

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Description

NADPH oxidase 2 (NOX2) inhibitor

GSK 2795039 is a NADPH oxidase 2 (NOX2) inhibitor (pIC50 value is 5.5 to 6.5, depending on assay performed), which displays selectivity for NOX2 other NOX isoforms, xanthine oxidase and eNOS. GSK 2795039 inhibits reactive oxygen species (ROS) in cellular assays, and displays efficacy in rodent models of paw inflammation and acute pancreatitis.
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Specifications

Chemical Name or Material N-[3-(2,3-Dihydro-1-methyl-1 H-indol-6-yl)-1-(1-methylethyl)-1 H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1 H-pyrazole-3-sulfonamide
CAS 1415925-18-6
Quantity 25 mg
Target NADPH Oxidase Inhibitors
Molecular Formula C23H26N6O2S
Purity 0.98
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