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Tocris Bioscience™ GSK 1562590 hydrochloride
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Product Code. 18785919
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 18785919

Brand: Tocris Bioscience™ 5110/10

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This item is not returnable. View return policy

High affinity, selective urotensin II (UT) receptor antagonist

GSK 1562590 hydrochloride is a high affinity and selective urotensin II (UT) receptor antagonist (pKi values are 9.14, 9.28, 9.34, 9.64 and 9.66 at monkey, human, mouse, cat and rat recombinant receptors respectively). Exhibits selectivity for UT receptors over a range of GPCRs, ion channels, enzymes and neurotransmitter transporters. Supresses human urotensin-II (hU-II)-induced contraction of isolated rat aorta in vitro and ex vivo. Inhibits the hU-II-induced increase in mean blood pressure in vivo. Orally active.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type GSK 1562590 hydrochloride
Purity >98%
Molecular Weight (g/mol) 617.95
Inhibitors GSK 1562590 hydrochloride

For Research Use Only

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