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Tocris Bioscience™ GRI 977143
Description
Selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 μM). Does not activate other LPA GPCRs at concentrations up to 10 μM. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activates ERK1/2 survival pathway.
Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 391.44 |
| Purity | >98% |
| Molecular Weight (g/mol) | 391.441 |
| Chemical Name or Material | GRI 977143 |
Product Title
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