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Invitrogen™ GRB2 Monoclonal Antibody (11-B11)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA534887
This item is not returnable.
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Description
Positive Control: 293, MCF-7, HepG2, rat brain tissue, human colon cancer tissue,.
GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.
Specifications
| GRB2 | |
| Monoclonal | |
| 2 mg/mL | |
| PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4 | |
| P62993 | |
| GRB2 | |
| Recombinant protein within Human GRB2 aa 21-217. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 11-B11 | |
| Unconjugated | |
| GRB2 | |
| AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg | |
| Mouse | |
| Protein G | |
| RUO | |
| 2885 | |
| -20°C, Avoid Freeze/Thaw Cycles, store in dark | |
| Liquid |
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