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Invitrogen™ GM-CSF Monoclonal Antibody (6804)
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Código de producto. 15523392
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Quantity:
500 μg
Tamaño de la unidad:
500µg
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15523392 500 μg 500µg
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Código de producto. 15523392 Proveedor Invitrogen™ N.º de proveedor MA523699

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Mouse Monoclonal Antibody

In ELISAs, this antibody does not cross-react with recombinant mouse (rm) GM-CSF, rrGM-CSF, rhM-CSF, rhG-CSF, rhIL-5-R alpha, or rhIL-3 R alpha. Reconstitute at 0.5 mg/mL in sterile PBS.

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
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Especificaciones

Antigen GM-CSF
Applications ELISA, Flow Cytometry
Classification Monoclonal
Clone 6804
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CSF2
Gene Accession No. P04141
Gene Alias colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
Gene Symbols CSF2
Host Species Mouse
Immunogen E. coli-derived recombinant human GM-CSF Ala18-Glu144.
Purification Method Protein A/G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1437
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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