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Invitrogen™ GLRX2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA566066
This item is not returnable.
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Description
Immunogen sequence: AAASGMESNTS SSLENLATAP VNQIQETISD NCVVIFSKTS CSYCTMA Highest antigen sequence identity to the following orthologs - mouse 73%, rat 73%.
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kD dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.
Specifications
| GLRX2 | |
| Polyclonal | |
| Unconjugated | |
| GLRX2 | |
| 1700010P22Rik; AI645710; bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); CGI-133; GLRX2; glutaredoxin (thioltransferase) 2; glutaredoxin 2; glutaredoxin 2 (thioltransferase); glutaredoxin-2, mitochondrial; GRX2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 51022 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9NS18 | |
| GLRX2 | |
| Recombinant Human GLRX2. Recombinant protein control fragment (Product #RP-106759). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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