missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ GBR 12909 dihydrochloride

Tocris Bioscience™ GBR 12909 dihydrochloride

Product Code. 18767696
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 18767696

Brand: Tocris Bioscience™ 0421/10

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Selective DA uptake inhibitor; also σ ligand

GBR 12909 dihydrochloride is a potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has >100-fold lower affinity for the noradrenaline and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
CAS 67469-78-7
Assay Percent Range >98%
Quantity 10 mg
Solubility Soluble to 50mM in DMSO
Molecular Formula C28H32F2N2O.2HCl
Formula Weight Observed MW: 523.49

For Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.