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Futibatinib, MedChemExpress

Product Code. 16485907
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Product Code. 16485907 Supplier Medchem Express Supplier No. HY1008185mg

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Description

MedChemExpress Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM).

Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGFR2=0.9 nM

Specifications

Chemical Name or Material Futibatinib
CAS 1448169-71-8
Color Off-White
Purity Grade Notes Research
Molecular Formula C22H22N6O3
Quantity 5 mg
Synonym TAS-120
Solubility Information DMSO : ≥ 29 mg/mL (69.30 mM)
SMILES O=C(C=C)N(C1)CC[C@@H]1N(N=C2C#CC3=CC(OC)=CC(OC)=C3)C4=C2C(N)=NC=N4
Molecular Weight (g/mol) 418.45
Formula Weight 418.45
Percent Purity 98.02%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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