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  6. Invitrogen™ FSTL3 Polyclonal Antibody

Invitrogen™ FSTL3 Polyclonal Antibody
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Product Code. 17780534
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200 μL
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200µL
20µL
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Product Code. Quantity unitSize
17780534 200 μL 200µL
17783374 20 μL 20µL
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Product Code. 17780534 Supplier Invitrogen™ Supplier No. PA5119126

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Description

Rabbit Polyclonal Antibody

FSTL3 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Follistatin-like 3 (FSTL3) is a gene located on chromosome 19p13.3 and encodes a secreted glycoprotein that belongs to the follistatin-related protein family. FSTL3 functions as an antagonist to members of the transforming growth factor-beta (TGF-β) superfamily, particularly inhibiting activin and myostatin signaling. This inhibitory action is crucial for regulating muscle growth, fertility, and inflammation. FSTL3 is expressed in various tissues, including the placenta, gonads, and skeletal muscle, where it modulates physiological processes by binding to and neutralizing the activities of its target ligands. Dysregulation of FSTL3 has been implicated in conditions such as muscle wasting, metabolic syndrome, and reproductive disorders, reflecting its role in maintaining tissue homeostasis and function. Research into FSTL3 focuses on its potential therapeutic applications in diseases involving TGF-β pathway dysregulation, offering insights into strategies for modulating growth factor activities in clinical settings.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FSTL3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene FSTL3
Gene Accession No. Q9EQC7
Gene Alias E030038F23Rik; FLRG; FLRGFSRP; follistatin like 3; follistatin-like 3; follistatin-like 3 (secreted glycoprotein); follistatin-like protein 3; Follistatin-related gene protein; follistatin-related protein 3; FSRP; FSTL3; UNQ674/PRO1308
Gene Symbols FSTL3
Host Species Rabbit
Immunogen Recombinant protein Follistatin Like Protein 3. The antigen corresponds to amino acid range 24-256 of the target protein.
Purification Method Antigen affinity chromatography, Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 83554
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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