missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Antibody Panels and Kits
  5. 15570707

Anti-Human Foxp3 Staining Set PE, eBioscience™

Product Code. 15570707
Change view
Click to view available options
Quantity:
1 kit
Unit Size:
1 set
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
15570707 1 kit 1 set
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 15570707 Supplier Invitrogen Supplier No. 72577440

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Includes

  • Fixation/Permeabilization Concentrate (4X) (cat. 00-5123): 30mL, store at 2-8°C. Avoid agitation.
  • Fixation/Permeabilization Diluent (cat. 00-5223): 100mL, store at 2-8°C.
  • Permeabilization Buffer (10X) (cat. 00-8333): 100mL, store at 2-8°C. Note: The 10X Permeabilization Buffer has a natural tendency to precipitate, however, its function is not affected by this. To clarify, the solution can be filtered after dilution to 1x working solution.
  • Normal Mouse Serum (cat. 24-5544): 100 μL, store at 2-8°C.
  • Anti-Human Foxp3 PE (clone 236A/E7, cat. 12-4777): 25 tests, store at 2-8°C. Light-sensitive material.

Antibody Staining Kit

This Anti-Human Foxp3 Staining Set contains the buffers and monoclonal antibody necessary to successfully stain and identify Foxp3+ cells. The 236A/E7 monoclonal antibody reacts with human Foxp3, also known as FORKHEAD BOX P3, SCURFIN, and JM2. Foxp3 is a 49-55kDa protein and a member of the forkhead/winged-helix family of transcription factors. It was identified as the gene responsible for the X-linked lymphoproliferative disease observed in scurfy (sf) mice and in the human disorder, X-linked autoimmunity-allergic dysregulation syndrome (XLAAD). Constitutive expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg), and ectopic expression of Foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells.

The 236A/E7 antibody has been shown to crossreact with rhesus macaque, sooty mangabey, and cynomolgus Foxp3. 236A/E7 recognizes a different epitope of Foxp3 than PCH101 and 150D/E4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Foxp3
Applications Flow Cytometry
Classification Monoclonal
Clone 236A/E7
Conjugate PE
Gene Alias Forkhead Box P3, Scurfin, JM2
Host Species Mouse
Quantity 1 kit
Regulatory Status RUO
Primary or Secondary Primary
Target Species Cynomolgus, Human, Macaque, Monkey, Non-human Primate, Rhesus Monkey
Content And Storage Store at 2-8°C. Light sensitive material. Use within 6 months of opening or by date indicated on the bottle.
Isotype IgG1
Product Line eBioscience
Show More Show Less

For Research Use Only. Not for use in diagnostic procedures.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.