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Forodesine hydrochloride, MedChemExpress

Product Code. 16469547
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Product Code. 16469547 Supplier Medchem Express Supplier No. HY16209

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Description

MedChemExpress Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels.

Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels.

Specifications

Chemical Name or Material Forodesine hydrochloride
CAS 284490-13-7
Color Brown
Purity Grade Notes Research
Molecular Formula C11H15ClN4O4
Quantity 5 mg
Synonym BCX-1777 hydrochlorideImmucillin-H hydrochloride
Solubility Information H2O : 100 mg/mL (330.35 mM; Need ultrasonic) ∣DMSO : 10 mg/mL (33.03 mM; Need ultrasonic)
SMILES O=C1C(NC=C2[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)=C2NC=N1.Cl
Molecular Weight (g/mol) 302.71
Formula Weight 302.71
Percent Purity 98.35%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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