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Invitrogen™ FANCD2 Recombinant Rabbit Monoclonal Antibody (23GB5365), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA552846
This item is not returnable.
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Description
FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability. It promotes accurate and efficient pairing of homologs during meiosis. FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing. It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress. FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin. Defects in the FANCD2 gene result in Fanconi anemia complementation group D2. This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.
Specifications
| FANCD2 | |
| Recombinant Monoclonal | |
| Unconjugated | |
| FANCD2 | |
| 2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 211651, 2177, 312641 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB5365 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q6IV68, Q80V62, Q9BXW9 | |
| FANCD2 | |
| A synthesized peptide derived from human FANCD2 (200-255AA). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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