missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Proteins and Derivatives
  5. Native Proteins and Derivatives
  6. 11564111

Invitrogen™ Human Factor XI Native Protein

Product Code. 11564111
Click to view available options
Quantity:
50 μg
Unit Size:
50µg
This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Product Code. 11564111

Brand: Invitrogen™ RP43075

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Description

Native Protein

RP-43075 contains native human Factor XI protein. RP-43075 may be used as a positive control in many immunological assays. The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P03951
Concentration 7.0 mg/mL
For Use With (Application) Control
Formulation 50% water with 50% glycerol and no preservative
Gene ID (Entrez) 2160
Molecular Weight (g/mol) 160 kDa
Name Human Factor XI
Quantity 50 μg
Source Human
Regulatory Status RUO
Gene Alias 1600027G01Rik; AI503996; Cf11; Coagulation factor XI; Coagulation factor XIa heavy chain; Coagulation factor XIa light chain; F11; FXI; LRRGT00086; plasma thromboplastin antecedent; PTA
Common Name Factor XI
Gene Symbol F11
Biological Activity Specific Activity =372 U/mg; determined by Factor XI clotting assay where 1 U equals the Factor XI activity in 1 mL of normal human plasma.
Conjugate Unconjugated
Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Form Liquid
Protein Subtype Native
Show More Show Less
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.