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  6. F4/80 Rat, anti-Mouse, Biotin, Clone: BM8, STEMCELL Technologies

F4/80 Rat, anti-Mouse, Biotin, Clone: BM8, STEMCELL Technologies

Product Code. 17138591
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500 μg
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17138591 50 μg 50µg
17128591 500 μg 500µg
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Product Code. 17138591 Supplier Stemcell Technologies Supplier No. 60027BT.1

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Description

Rat Monoclonal Antibody

  • The BM8 antibody reacts with the F4/80 antigen (also termed Ly-71 in mouse and EMR-1 in human), an ∼160 kDa transmembrane glycoprotein belonging to the EGF-TM7 family of G-protein-coupled receptors
  • F4/80 is considered a marker of choice for the identification of mature tissue macrophages, being broadly but variably expressed by this cell type in the liver (Kupffer cells), skin (Langerhans cells), bone marrow stroma, pancreas, thymus, spleen (red pulp), lung, and other tissues
  • It is also expressed by circulating monocytes, eosinophils and a subset of dendritic cells
  • F4/80 is reportedly the only macrophage marker suitable for distinguishing destructive from non-destructive inflammatory processes in the pancreas
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse Monocyte Enrichment Kit (Catalog #19761) and EasySep™ Mouse CD11b Positive Selection Kit (Catalog #18770)

Specifications

Antigen F4/80
Applications Immunohistochemistry, Western Blot, ELISA, Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone BM8
Conjugate Biotin
Host Species Rat
Quantity 50 μg
Primary or Secondary Primary
Target Species Human, Mouse
Isotype IgG2a κ
Cell Type Monocytes, Other
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