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  5. Tocris Bioscience™ ERK5-IN-1

Tocris Bioscience™ ERK5-IN-1
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Product Code. 18747068
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18747068

Brand: Tocris Bioscience™ 5393/10

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Description

Potent and selective ERK5 inhibitor

ERK5-IN-1 is a potent and selective ERK5 inhibitor; inhibits EGFR-induced ERK5 autophosphorylation (EC50 = 90 nM) and ERK5 enzymatic activity (IC50 = 162 nM). Exhibits at least 30-fold selectivity for ERK5 over LRRK2 in a cell based assay. Also selective for ERK5 over a panel of other kinases. Orally bioavailable.
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Specifications

Purity >98%
Description ERK5-IN-1
Molecular Weight (g/mol) 638.8
Product Type ERK5-IN-1
Quantity 10 mg

For Research Use Only

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