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EMR1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16805345 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16805345 20 μL 20µL
16895335 150 μL 150µL
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Product Code. 16805345 Supplier Proteintech Supplier No. 270441AP20UL

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Description

Rabbit Polyclonal Antibody

F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.

Specifications

Antigen EMR1
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ADGRE1
Gene Accession No. Q14246, Q61549
Gene Alias ADGRE1, Adhesion G protein-coupled receptor E1, EGF like module receptor 1, EMR1, EMR1 hormone receptor, F4/80, TM7LN3
Gene Symbols ADGRE1
Host Species Rabbit
Immunogen EMR1 Fusion Protein Ag25883
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13733, 2015
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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