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ELOVL6 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA513455
Additional Details : Weight : 0.01000kg
Description
This antibody is predicted to react with chicken and rat based on sequence homology.
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.Specifications
ELOVL6 | |
Polyclonal | |
Unconjugated | |
ELOVL6 | |
3-keto acyl-CoA synthase Elovl6; C77826; Elongation of very long chain fatty acids protein 6; ELOVL FA elongase 6; ELOVL family member 6, elongation of long chain fatty acids; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast); ELOVL family member 6, elongation of long chain fatty acids (yeast); ELOVL fatty acid elongase 6; ELOVL6; FACE; FAE; fatty acid elongase 2; Fatty acyl-CoA elongase; hELO2; Lce; Lce2; long chain fatty acid elongase; long chain fatty acyl elongase; long-chain fatty-acyl elongase; Masr; Myelin-associated SUR4 protein; rELO2; Very long chain 3-ketoacyl-CoA synthase 6; very long chain 3-oxoacyl-CoA synthase 6; very-long-chain 3-oxoacyl-CoA synthase 6 | |
Rabbit | |
Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
RUO | |
170439, 79071 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
2 mg/mL | |
PBS with 0.09% sodium azide | |
Q920L5, Q9H5J4 | |
ELOVL6 | |
KLH conjugated synthetic peptide between 32-58 amino acids from the N-terminal region of human ELOVL6 | |
400 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |