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STEMCELL Technologies EC23
Retinoid pathway activator; Activates retinoic acid receptor (RAR)
44.55 € - 168.75 €
Specifications
| CAS | 104561-41-3 |
|---|---|
| Synonym | AGN 190205; BASF 46928 |
| Molecular Formula | C23H24O2 |
| Purity | ≥98% |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17140172
|
STEMCELL Technologies
73102 |
1 mg |
44.55 €
1mg |
Estimated Shipment: 31-07-2024 Log in to see stock. |
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|
17150172
|
STEMCELL Technologies
73104 |
10 mg |
168.75 €
10mg |
Estimated Shipment: 31-07-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
- EC23 is a retinoic acid receptor (RAR) agonist with pan-RAR activity (EC50: RARα 41 nM, RARβ 0.5 nM, RARγ 0.4 nM), while having no appreciable activity for retinoid X receptors (RXR; EC50> 10μM for all; Gambone et al.) It is a photostable synthetic analog of all-trans retinoic acid (ATRA; Christie et al. 2008)
- EC23 also weakly activates aryl hydrocarbon receptor (Gambone et al.)
- Induces neural differentiation of human pluripotent stem cells, similarly to ATRA (Christie et al. 2010; Clemens et al.)
- Induces neuronal differentiation of human fetal neural progenitor cell line ReNcell 197VM (Christie et al. 2010)
Specifications
| 104561-41-3 | |
| AGN 190205; BASF 46928 | |
| C23H24O2 | |
| ≥98% |