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STEMCELL Technologies EC23

Retinoid pathway activator; Activates retinoic acid receptor (RAR)

44.55 € - 168.75 €

Specifications

CAS 104561-41-3
Synonym AGN 190205; BASF 46928
Molecular Formula C23H24O2
Purity ≥98%
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
17140172
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STEMCELL Technologies
73102
1 mg
44.55 €
1mg
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17150172
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STEMCELL Technologies
73104
10 mg
168.75 €
10mg
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Estimated Shipment: 25-06-2024
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Description

Description

  • EC23 is a retinoic acid receptor (RAR) agonist with pan-RAR activity (EC50: RARα 41 nM, RARβ 0.5 nM, RARγ 0.4 nM), while having no appreciable activity for retinoid X receptors (RXR; EC50> 10μM for all; Gambone et al.) It is a photostable synthetic analog of all-trans retinoic acid (ATRA; Christie et al. 2008)
  • EC23 also weakly activates aryl hydrocarbon receptor (Gambone et al.)
  • Induces neural differentiation of human pluripotent stem cells, similarly to ATRA (Christie et al. 2010; Clemens et al.)
  • Induces neuronal differentiation of human fetal neural progenitor cell line ReNcell 197VM (Christie et al. 2010)
Specifications

Specifications

104561-41-3
AGN 190205; BASF 46928
C23H24O2
≥98%
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