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Tocris Bioscience™ DX3-213B

Product Code. 30040319
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10 mg
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10mg
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Product Code. 30040319 Supplier Tocris Bioscience™ Supplier No. 8070/10

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265.20 EUR valid until 2026-03-31
BEST PRICE on Promo! Use promo code "27931" to get your promotional price.
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Description

Potent NDUFS7 antagonist

DX3-213B is a potent oxidative phosphorylation (OXPHOS) complex I (also known as NDUFS7) antagonist (IC50 = 3.6 nM). DX3-213B impairs ATP generation (IC50 = 11 nM) and inhibits the proliferation of MIA PaCa-2 cells (IC50 = 9 nM) in galactose-containing media. In vivo, DX3-213B significantly delays tumor growth in a syngeneic mouse model of pancreatic cancer. DX3-213B is orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (4,4-Difluoro-1-piperidinyl)[(3R)-1-[[4-[(1-methylethyl)sulfonyl]phenyl]sulfonyl]-3-piperidinyl]methanone
CAS 2749555-66-4
Quantity 10 mg
Target Oxidative Phosphorylation Inhibitors
Molecular Formula C20H28F2N2O5S2
Purity 0.97
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