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Description
Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis. It is a holoenzyme shell (approximately 450 kDa) consisting of 24 subunits of two types, H (heavy) and L (light), and capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiologic status of the cell, the ratio of H to L subunits in ferritin can vary widely. It can be viewed not only as part of a group of iron regulatory proteins that include transferrin and the transferrin receptor, but also as a member of the protein family that orchestrates the cellular defense against stress and inflammation. Ferritin is found in the liver, spleen, kidney and heart. Only a small amount is found in the blood. The blood level of ferritin serves as an indicator of the amount of iron stored in the body.
Specifications
Specifications
| Antigen | DTD1 |
| Applications | Immunofluorescence, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.15 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | DTD1 |
| Gene Accession No. | Q8TEA8, Q9DD18 |
| Gene Alias | C20orf88, DTD1, DUEB, HARS2, Histidyl tRNA synthase related, pqn 68 |
| Gene Symbols | Dtd1 |
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Product Title
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