missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 17100122

STEMCELL Technologies Doxycycline (Hyclate)

Product Code. 17100122
Encompass_Preferred
Change view
Click to view available options
Quantity:
1 g
Unit Size:
1g
Product Code. Quantity unitSize
17100122 1 g 1g
1 options
This item is not returnable. View return policy

Product Code. 17100122

Brand: STEMCELL Technologies 72742

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Antibiotic; Used in Tet-inducible gene expression systems

  • Doxycycline is a tetracycline-like antibiotic (Hicks et al.; Nau et al.; Solís García del Pozo & Solera; Steinhardt et al.) In genetic engineering, doxycycline is used as the regulator for inducible gene expression systems, whereby expression depends on either the presence (Tet-On) or absence (Tet-Off ) of doxycycline
  • Also, doxycycline inhibits certain matrix metalloproteinases (MMP), such as MMP-8 (Ki = 36 μM; Griffin et al.; Smith et al.) It only poorly inhibits MMP-1 and MMP-13 (Ki > 100 μM; Smith et al.) This product is supplied as the hyclate salt of the molecule
  • Used as the regulator for inducible gene expression in lentiviral infection and transgenic mouse models using the Tet-On or Tet-Off systems (Brambrink et al.; Carey et al.; Haenebalcke et al.; Hanna et al.; Hockemeyer et al.; Maherali et al.; Markoulaki et al.; Stadtfeld et al. 2008, 2010; Wernig et al.)

Specifications

CAS 24390-14-5
Synonym WC 2031
Quantity 1 g
Molecular Formula 2[C22H24N2O8] · 2HCl · H2O · C2H6O
Purity ≥98%
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.