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DMAP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10411-1-AP-20UL

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Product Code. 16846783

  • 145.00 € / 20µL

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Description

Description

The antibody reacts specifically with DMAP1 protein.

DNA methyltransferase 1-associated protein 1 (DMAP1) is involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The protein also specifically potentiates DAXX-mediated repression of glucocorticoid receptor-dependent transcription. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. DMAP1 is found in a wide variety of living organisms from yeasts to humans. The human DMAP1 gene is localized on chromosome 1p34.
Spécification

Spécification

DMAP1
Polyclonal
Unconjugated
DMAP1
DMAP1, DNMAP1, DNMT1 associated protein 1, DNMTAP1, EAF2, KIAA1425, SWC4
Rabbit
Antigen Affinity Chromatography
RUO
298447, 55929, 66233
-20°C
Liquid
Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
0.29 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9JI44, Q9NPF5
DMAP1
DMAP1 Fusion Protein Ag0665
20 μL
Primary
Mouse, Human, Rat
Antibody
IgG
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